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Issue 24, 2011
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Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

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Abstract

The catalytic asymmetric 1,3-dipolar cycloaddition of azomethine ylides constitutes one of the most powerful and atom economical methods for the enantioselective construction of pyrrolidines. This article highlights the recent developments in this area, with special focus on contributions improving the structural scope at the dipolarophile and azomethine ylide partners.

Graphical abstract: Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

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Publication details

The article was received on 10 Feb 2011, accepted on 15 Mar 2011 and first published on 06 Apr 2011


Article type: Feature Article
DOI: 10.1039/C1CC10779H
Citation: Chem. Commun., 2011,47, 6784-6794
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    Novel dipolarophiles and dipoles in the metal-catalyzed enantioselective 1,3-dipolar cycloaddition of azomethine ylides

    J. Adrio and J. C. Carretero, Chem. Commun., 2011, 47, 6784
    DOI: 10.1039/C1CC10779H

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