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Issue 15, 2011
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Controllable exploding microcapsules as drug carriers

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Controllable exploding polyelectrolyte microcapsules were developed by layer-by-layer assembly of poly(allylamine hydrochloride) (PAH) and poly(sodium 4-styrenesulfonate) (PSS) on a dextran microgel core containing a cleavable disulfide bond fabricated via click chemistry. The microcapsules can explode upon the injection of DTT with an explosive release of the drug.

Graphical abstract: Controllable exploding microcapsules as drug carriers

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Publication details

The article was received on 18 Jan 2011, accepted on 22 Feb 2011 and first published on 09 Mar 2011

Article type: Communication
DOI: 10.1039/C1CC10337G
Citation: Chem. Commun., 2011,47, 4457-4459
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    Controllable exploding microcapsules as drug carriers

    J. Zhang, C. Li, Y. Wang, R. Zhuo and X. Zhang, Chem. Commun., 2011, 47, 4457
    DOI: 10.1039/C1CC10337G

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