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Issue 14, 2011
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Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells

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Abstract

We explore the long-term stability of two different classes of labelled nanoparticles as intracellular SE(R)RS probes. Whilst chemisorbed labels gave stable responses inside cells for extended periods of time, signals from physisorbed labels could only be measured for short periods of time. These results help inform strategies for cellular imaging using vibrational spectroscopies.

Graphical abstract: Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells

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Publication details

The article was received on 22 Dec 2010, accepted on 14 Feb 2011 and first published on 28 Feb 2011


Article type: Communication
DOI: 10.1039/C0CC05723A
Citation: Chem. Commun., 2011,47, 4099-4101
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    Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells

    N. M. S. Sirimuthu, C. D. Syme and J. M. Cooper, Chem. Commun., 2011, 47, 4099
    DOI: 10.1039/C0CC05723A

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