Jump to main content
Jump to site search

Issue 19, 2011
Previous Article Next Article

Unexpected C–C bond cleavage of epoxide motif: Rhodium(I)-catalyzed tandem heterocyclization/[4+1] cycloaddition of 1-(1-alkynyl)oxiranyl ketones

Author affiliations

Abstract

A rhodium(I)-catalyzed tandem heterocyclization and formal [4+1] cycloaddition of 1-(1-alkynyl)oxiranyl ketones was developed, which provides a general, efficient and practical route to highly substituted furo[3,4-b]furan-3(2H)-ones, wherein the epoxide motif undergo unexpected C–C bond cleavage rather than the classical C–O bond cleavage.

Graphical abstract: Unexpected C–C bond cleavage of epoxide motif: Rhodium(i)-catalyzed tandem heterocyclization/[4+1] cycloaddition of 1-(1-alkynyl)oxiranyl ketones

Back to tab navigation

Supplementary files

Publication details

The article was received on 17 Dec 2010, accepted on 23 Mar 2011 and first published on 06 Apr 2011


Article type: Communication
DOI: 10.1039/C0CC05650B
Citation: Chem. Commun., 2011,47, 5578-5580
  •   Request permissions

    Unexpected C–C bond cleavage of epoxide motif: Rhodium(I)-catalyzed tandem heterocyclization/[4+1] cycloaddition of 1-(1-alkynyl)oxiranyl ketones

    T. Wang, C. Wang and J. Zhang, Chem. Commun., 2011, 47, 5578
    DOI: 10.1039/C0CC05650B

Search articles by author

Spotlight

Advertisements