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Issue 13, 2011
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Copper(II)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides

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Abstract

Copper-catalyzed ortho-benzoxylation of 2-arylpyridine sp2 C–H bonds with acyl chloride is described. Notably, switching the base from t-BuOK to Li2CO3 causes chlorination of the C–H bond to take place.

Graphical abstract: Copper(ii)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides

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Publication details

The article was received on 14 Dec 2010, accepted on 14 Feb 2011 and first published on 28 Feb 2011


Article type: Communication
DOI: 10.1039/C0CC05557C
Citation: Chem. Commun., 2011,47, 3978-3980
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    Copper(II)-catalyzed ortho-functionalization of 2-arylpyridines with acyl chlorides

    W. Wang, C. Pan, F. Chen and J. Cheng, Chem. Commun., 2011, 47, 3978
    DOI: 10.1039/C0CC05557C

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