Jump to main content
Jump to site search

Issue 7, 2011
Previous Article Next Article

Proteinligand binding investigated by a single nanoparticle TERS approach

Author affiliations

Abstract

We report TERS imaging of individual 50 nm, biotin-labeled gold nanoparticles bound to a streptavidin-derivatized glass slide. Individual gold nanoparticles detected by a nanoparticle TERS tip generate Raman enhancements in both the biotin and streptavidin signals. These results indicate that nanoparticles are capable of investigating nanoscale spatial and chemical environments with non-resonant Raman enhancements.

Graphical abstract: Protein–ligand binding investigated by a single nanoparticle TERS approach

Back to tab navigation

Supplementary files

Publication details

The article was received on 19 Nov 2010, accepted on 10 Dec 2010 and first published on 04 Jan 2011


Article type: Communication
DOI: 10.1039/C0CC05059H
Citation: Chem. Commun., 2011,47, 2065-2067
  •   Request permissions

    Proteinligand binding investigated by a single nanoparticle TERS approach

    S. L. Carrier, C. M. Kownacki and Z. D. Schultz, Chem. Commun., 2011, 47, 2065
    DOI: 10.1039/C0CC05059H

Search articles by author

Spotlight

Advertisements