Issue 11, 2011

Functionalisation of aldehydesvia aerobic hydroacylation of azodicarboxylates ‘on’ water

Abstract

Herein we report the functionalisation of aldehydesvia hydroacylation of azodicarboxylates. A range of functionalised aldehydes are employed as the limiting reagent including chiral non-racemic aldehydes bearing α-stereocentres which are functionalised giving access to enantiomerically pure products. The resultant hydrazides can be employed as acyl donors in the synthesis of amides.

Graphical abstract: Functionalisation of aldehydesvia aerobic hydroacylation of azodicarboxylates ‘on’ water

Supplementary files

Article information

Article type
Communication
Submitted
20 Oct 2010
Accepted
21 Dec 2010
First published
01 Feb 2011

Chem. Commun., 2011,47, 3269-3271

Functionalisation of aldehydesvia aerobic hydroacylation of azodicarboxylates ‘on’ water

V. Chudasama, J. M. Ahern, D. V. Dhokia, R. J. Fitzmaurice and S. Caddick, Chem. Commun., 2011, 47, 3269 DOI: 10.1039/C0CC04520A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements