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Issue 7, 2011
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Osmium(VI) complexes as a new class of potential anti-cancer agents

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Abstract

A nitridoosmium(VI) complex [OsVI(N)(sap)(OH2)Cl] (H2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate.

Graphical abstract: Osmium(vi) complexes as a new class of potential anti-cancer agents

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Publication details

The article was received on 20 Oct 2010, accepted on 06 Dec 2010 and first published on 04 Jan 2011


Article type: Communication
DOI: 10.1039/C0CC04515B
Citation: Chem. Commun., 2011,47, 2140-2142
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    Osmium(VI) complexes as a new class of potential anti-cancer agents

    W. Ni, W. Man, M. T. Cheung, R. W. Sun, Y. Shu, Y. Lam, C. Che and T. Lau, Chem. Commun., 2011, 47, 2140
    DOI: 10.1039/C0CC04515B

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