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Issue 13, 2011
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A sensitive and selective resonance light scattering bioassay for homocysteine in biological fluids based on target-involved assembly of polyethyleneimine-capped Ag-nanoclusters

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Abstract

A specific resonance light scattering bioassay for homocysteine is developed on the basis of target-involved assembly of polyethyleneimine-capped Ag-nanoclusters. The bioassay permits discriminating homocysteine from cysteine, glutathione and other amino acids, and allows sensitive and selective detection of homocysteine with a detection limit of 42 nM.

Graphical abstract: A sensitive and selective resonance light scattering bioassay for homocysteine in biological fluids based on target-involved assembly of polyethyleneimine-capped Ag-nanoclusters

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Publication details

The article was received on 17 Oct 2010, accepted on 12 Jan 2011 and first published on 02 Feb 2011


Article type: Communication
DOI: 10.1039/C0CC04463F
Citation: Chem. Commun., 2011,47, 3817-3819
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    A sensitive and selective resonance light scattering bioassay for homocysteine in biological fluids based on target-involved assembly of polyethyleneimine-capped Ag-nanoclusters

    S. Sun, H. Wang and X. Yan, Chem. Commun., 2011, 47, 3817
    DOI: 10.1039/C0CC04463F

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