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Issue 1, 2011
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Efficient and scalable serial extraction of DNA and RNA from frozen tissue samples

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Abstract

Advances in cancer genomics have created a demand for scalable sample processing. We here present a process for serial extraction of nucleic acids from the same frozen tissue sample based on magnetic silica particles. The process is automation friendly with high recoveries of pure DNA and RNA suitable for analysis.

Graphical abstract: Efficient and scalable serial extraction of DNA and RNA from frozen tissue samples

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Publication details

The article was received on 30 Jun 2010, accepted on 08 Nov 2010 and first published on 23 Nov 2010


Article type: Communication
DOI: 10.1039/C0CC02248A
Citation: Chem. Commun., 2011,47, 547-549
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    Efficient and scalable serial extraction of DNA and RNA from frozen tissue samples

    L. Mathot, M. Lindman and T. Sjöblom, Chem. Commun., 2011, 47, 547
    DOI: 10.1039/C0CC02248A

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