Issue 1, 2011

Efficient and scalable serial extraction of DNA and RNA from frozen tissue samples

Abstract

Advances in cancer genomics have created a demand for scalable sample processing. We here present a process for serial extraction of nucleic acids from the same frozen tissue sample based on magnetic silica particles. The process is automation friendly with high recoveries of pure DNA and RNA suitable for analysis.

Graphical abstract: Efficient and scalable serial extraction of DNA and RNA from frozen tissue samples

Supplementary files

Article information

Article type
Communication
Submitted
30 Jun 2010
Accepted
08 Nov 2010
First published
23 Nov 2010

Chem. Commun., 2011,47, 547-549

Efficient and scalable serial extraction of DNA and RNA from frozen tissue samples

L. Mathot, M. Lindman and T. Sjöblom, Chem. Commun., 2011, 47, 547 DOI: 10.1039/C0CC02248A

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