Ferritin and metallothionein: dangerous liaisons†
Abstract
Ferritin (Ft) interaction with the Zn-complexes of mammalian MT1, MT2 and MT3 metallothioneins (MT) leads to simultaneous FeII and ZnII release.
* Corresponding authors
a
Dept. Química, Universitat Autònoma de Barcelona, 08193 Cerdanyola del Vallès, Barcelona, Spain
E-mail:
merce.capdevila@.uab.cat
b Instituto de Parasitología y Biomedicina “Lopez-Neyra”, Parque Tecnológico Ciencias de la Salud, 18100 Armilla, Granada, Spain
c
Dept. Química Inorgánica, Fac. Ciencias, Universidad de Granada, 18071 Granada, Spain
E-mail:
josema@ugr.es
d Dept. Genètica, Fac. Biologia, Universitat de Barcelona, and IBUB, Av. Diagonal 645, Barcelona, Spain
e Dept. Chemistry and Biochemistry, Brigham Young University, Provo, USA
Ferritin (Ft) interaction with the Zn-complexes of mammalian MT1, MT2 and MT3 metallothioneins (MT) leads to simultaneous FeII and ZnII release.
R. Orihuela, B. Fernández, Ò. Palacios, E. Valero, S. Atrian, R. K. Watt, J. M. Domínguez-Vera and M. Capdevila, Chem. Commun., 2011, 47, 12155 DOI: 10.1039/C1CC14819B
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