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Issue 38, 2011
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Patterning small-molecule biocapture surfaces: microcontact insertion printing vs.photolithography

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Abstract

Chemical patterns prepared by self-assembly, combined with soft lithography or photolithography, are directly compared. Pattern fidelity can be controlled in both cases but patterning at the low densities necessary for small-molecule probe capture of large biomolecule targets is better accomplished using microcontact insertion printing (μCIP). Surfaces patterned by μCIP are used to capture biomolecule binding partners for the small molecules dopamine and biotin.

Graphical abstract: Patterning small-molecule biocapture surfaces: microcontact insertion printing vs.photolithography

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Publication details

The article was received on 23 May 2011, accepted on 27 Jul 2011 and first published on 26 Aug 2011


Article type: Communication
DOI: 10.1039/C1CC13002A
Citation: Chem. Commun., 2011,47, 10641-10643
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    Patterning small-molecule biocapture surfaces: microcontact insertion printing vs.photolithography

    M. J. Shuster, A. Vaish, H. H. Cao, A. I. Guttentag, J. E. McManigle, A. L. Gibb, M. M. Martinez, R. M. Nezarati, J. M. Hinds, W.-S. Liao, P. S. Weiss and A. M. Andrews, Chem. Commun., 2011, 47, 10641
    DOI: 10.1039/C1CC13002A

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