Issue 22, 2011
From the journal:

Chemical Communications

Decarboxylative formation of N-alkyl pyrroles from 4-hydroxyproline†

Indubhusan Deb,a   Daniel J. Coiroa  and  Daniel Seidel*a  

* Corresponding authors

a Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, 610 Taylor Road, Piscataway, New Jersey 08854, USA
E-mail: seidel@rutchem.rutgers.edu

Abstract

N-Alkyl pyrroles are obtained in a single step from 4-hydroxyproline and aldehydes in just 15 min under microwave irradiation.

Graphical abstract: Decarboxylative formation of N-alkyl pyrroles from 4-hydroxyproline

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Article information

DOI
https://doi.org/10.1039/C1CC11560J
Article type
Communication
Submitted
17 Mar 2011
Accepted
18 Apr 2011
First published
09 May 2011

Chem. Commun., 2011,47, 6473-6475

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Decarboxylative formation of N-alkyl pyrroles from 4-hydroxyproline

I. Deb, D. J. Coiro and D. Seidel, Chem. Commun., 2011, 47, 6473 DOI: 10.1039/C1CC11560J

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