Issue 21, 2011
From the journal:

Chemical Communications

Ultrasensitive and selective DNA detection by hydroxylamine assisted gold nanoparticle amplification†

Sheng Cai,a   Liang Xin,a   Choiwan Lau,a   Jianzhong Lu*a  and  Xueji Zhang*b  

* Corresponding authors

a School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai, China
E-mail: jzlu@shmu.edu.cn
Fax: (+86) 21-51980058

b Department of Chemistry, University of South Florida, 4202 E. Fowler Ave. CHE-205A, Tampa, USA
E-mail: xzhang@cas.usf.edu
Fax: (+1) 941-3712534

Abstract

A new nanoparticle-based chemiluminescent (CL) method has been developed for the ultrasensitive detection of DNA hybridization which can achieve ultra-sensitivity up to approximately 30 zmol, i.e. 300 aM.

Graphical abstract: Ultrasensitive and selective DNA detection by hydroxylamine assisted gold nanoparticle amplification

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Article information

DOI
https://doi.org/10.1039/C1CC10914F
Article type
Communication
Submitted
16 Feb 2011
Accepted
04 Apr 2011
First published
21 Apr 2011

Chem. Commun., 2011,47, 6120-6122

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Ultrasensitive and selective DNA detection by hydroxylamine assisted gold nanoparticle amplification

S. Cai, L. Xin, C. Lau, J. Lu and X. Zhang, Chem. Commun., 2011, 47, 6120 DOI: 10.1039/C1CC10914F

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