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Issue 8, 2011
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Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection

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Abstract

We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.

Graphical abstract: Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection

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Publication details

The article was received on 07 Sep 2010, accepted on 16 Nov 2010 and first published on 09 Dec 2010


Article type: Communication
DOI: 10.1039/C0CC03711G
Citation: Chem. Commun., 2011,47, 2294-2296
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    Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection

    J. Sharma, H. Yeh, H. Yoo, J. H. Werner and J. S. Martinez, Chem. Commun., 2011, 47, 2294
    DOI: 10.1039/C0CC03711G

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