Issue 1, 2011

DNA–nanoparticle micelles as supramolecular fluorogenic substrates enabling catalytic signal amplification and detection by DNAzyme probes

Abstract

Catalytic DNA molecules have tremendous potential in propagating detection events vianucleic acid sequence selective signal amplification. However, they suffer from product inhibition limiting their widespread utility. Herein, this limitation is overcome utilizing a novel fluorogenic substrate design consisting of cooperatively assembled DNA–nanoparticle micelles.

Graphical abstract: DNA–nanoparticle micelles as supramolecular fluorogenic substrates enabling catalytic signal amplification and detection by DNAzyme probes

Supplementary files

Article information

Article type
Communication
Submitted
01 Jul 2010
Accepted
12 Aug 2010
First published
07 Sep 2010

Chem. Commun., 2011,47, 167-169

DNA–nanoparticle micelles as supramolecular fluorogenic substrates enabling catalytic signal amplification and detection by DNAzyme probes

M. Chien, M. P. Thompson and N. C. Gianneschi, Chem. Commun., 2011, 47, 167 DOI: 10.1039/C0CC02291H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements