Issue 1, 2011
From the journal:

Chemical Communications

Revisiting the Kinnel–Scheuer hypothesis for the biosynthesis of palau'amine†‡

Zhiqiang Ma,a   Jianming Lu,a   Xiao Wanga  and  Chuo Chen*a  

* Corresponding authors

a Department of Biochemistry, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, USA
E-mail: Chuo.Chen@UTSouthwestern.edu
Fax: 214 648 0320
Tel: 214 648 5048

Abstract

We propose herein an alternative biosynthetic pathway for palau'amine in order to resolve the stereochemical issue from the original Kinnel–Scheuer hypothesis. Furthermore, we use this revised hypothesis as a guide toward the laboratory synthesis of palau'amine.

Graphical abstract: Revisiting the Kinnel–Scheuer hypothesis for the biosynthesis of palau'amine

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Article information

DOI
https://doi.org/10.1039/C0CC02214D
Article type
Communication
Submitted
29 Jun 2010
Accepted
03 Sep 2010
First published
16 Sep 2010

Chem. Commun., 2011,47, 427-429

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Revisiting the Kinnel–Scheuer hypothesis for the biosynthesis of palau'amine

Z. Ma, J. Lu, X. Wang and C. Chen, Chem. Commun., 2011, 47, 427 DOI: 10.1039/C0CC02214D

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