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Issue 1, 2011
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Domino gold-catalyzed rearrangement and fluorination of propargyl acetates

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Abstract

A combination of IPrAuNTf2 as catalyst in the presence of Selectfluor has been successfully used for the high yielding synthesis of α-fluoroenones via 1,3-acyloxy rearrangement of propargyl acetates followed by Csp2–F bond formation, likely involving a redox Au(I)/Au(III) catalytic cycle.

Graphical abstract: Domino gold-catalyzed rearrangement and fluorination of propargyl acetates

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Publication details

The article was received on 10 Feb 2010, accepted on 28 May 2010 and first published on 29 Jun 2010


Article type: Communication
DOI: 10.1039/C002679D
Citation: Chem. Commun., 2011,47, 248-249
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    Domino gold-catalyzed rearrangement and fluorination of propargyl acetates

    T. de Haro and C. Nevado, Chem. Commun., 2011, 47, 248
    DOI: 10.1039/C002679D

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