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Issue 4, 2011
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Laser-based refractive index detection for micro-channels

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Abstract

Laser-based refractive index detection, based upon refractive index changes in micro-channels, is a kind of laser-based optical determination for solutions. As it is capable of label-free determination, it has been regarded as a considerable growth prospect. The key aspect in related researches lay in the development of novel detection configurations, which would possibly result in better sensitivity. Over the past decade, micro-channel laser-based refractive index detection has been significantly improved, resulting in traversed, hologram-based, back-scattered, retro-reflected interference, optical ring resonant, etc., detection configurations. Moreover, laser-based refractive index detection has been combined with other laser-based detection strategies, in order to pursue a universal and sensitive detection. And last but not least, some utilizations of laser-based refractive index detection have been reported, while both advantages and drawbacks exist. In this paper, laser-based refractive index detection for micro-channels will be reviewed in proceeding sequence.

Graphical abstract: Laser-based refractive index detection for micro-channels

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Publication details

The article was received on 02 Aug 2010, accepted on 18 Nov 2010 and first published on 08 Dec 2010


Article type: Minireview
DOI: 10.1039/C0AN00596G
Citation: Analyst, 2011,136, 635-641
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    Laser-based refractive index detection for micro-channels

    B. Xiong and J. Hu, Analyst, 2011, 136, 635
    DOI: 10.1039/C0AN00596G

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