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Issue 1, 2011
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Colorimetric detection of melamine in complex matrices based on cysteamine-modified gold nanoparticles

Xiaosheng Liang,ab  Hongping Wei,a  Zongqiang Cui,a  Jiaoyu Deng,a  Zhiping Zhang,a  Xiangyu Youab  and  Xian-En Zhang*a 
Author affiliations

* Corresponding authors

a State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China
E-mail: x.zhang@wh.iov.cn
Fax: +86 27 8719 9492
Tel: +86 27 8719 9115

b Graduate School, Chinese Academy of Sciences, Beijing, China

Abstract

A sensitive assay for melamine in complex matrices is built using cysteamine-modified gold nanoparticles (AuNPs) and an effective sample pretreatment protocol. Citrate-stabilized AuNPs were modified by cysteamine in order to weaken the electrostatic repulsion force between the gold nanoparticles. Detection sensitivity gained through this modification increased about 100 fold compared with the result using the unmodified AuNPs. Direct colorimetric visualizations of melamine in milk products, eggs and feeds was successfully demonstrated within the linear ranges of 1–200 mg L−1 and detection limits below 1 mg L−1. The proposed scheme could be an alternative means for onsite detection of melamine without costly instruments.

Graphical abstract: Colorimetric detection of melamine in complex matrices based on cysteamine-modified gold nanoparticles

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Publication details

The article was received on 22 Jun 2010, accepted on 02 Sep 2010 and first published on 29 Sep 2010


Article type: Paper
DOI: 10.1039/C0AN00432D
Citation: Analyst, 2011,136, 179-183
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    Colorimetric detection of melamine in complex matrices based on cysteamine-modified gold nanoparticles

    X. Liang, H. Wei, Z. Cui, J. Deng, Z. Zhang, X. You and X. Zhang, Analyst, 2011, 136, 179
    DOI: 10.1039/C0AN00432D

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