Issue 2, 2011
From the journal:

Chemical Science

Azomethine ylide annulations: facile access to polycyclic ring systems†

Chen Zhang,a   Deepankar Dasa  and  Daniel Seidel*a  

* Corresponding authors

a Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey, Piscataway, New Jersey
E-mail: seidel@rutchem.rutgers.edu

Abstract

New annulation reactions of azomethine ylides are reported. Amino acids react with aldehydes that are linked to a pronucleophile (e.g. an indole subunit) to provide rapid access to polycyclic ring systems. Simple amines can also be used in place of amino acids.

Graphical abstract: Azomethine ylide annulations: facile access to polycyclic ring systems

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Article information

DOI
https://doi.org/10.1039/C0SC00432D
Article type
Edge Article
Submitted
12 Aug 2010
Accepted
05 Oct 2010
First published
27 Oct 2010

Chem. Sci., 2011,2, 233-236

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Azomethine ylide annulations: facile access to polycyclic ring systems

C. Zhang, D. Das and D. Seidel, Chem. Sci., 2011, 2, 233 DOI: 10.1039/C0SC00432D

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