Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative

Alan R. Katritzky; Sevil Ozcan; Ekaterina Todadze

doi:10.1039/C000684J

Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative

Alan R. Katritzky,*^a Sevil Ozcan^a^b and Ekaterina Todadze^a

* Corresponding authors

^a Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, USA
E-mail: katritzky@chem.ufl.edu
Fax: +1 352-392-9199
Tel: +1 352-292-7022

^b Abant Izzet Baysal University, Department of Chemistry, Golkoy, Turkey

Abstract

Convenient and efficient synthesis of a new environmentally sensitive chlorine-substituted 2,3-naphthalimide-based fluorophore is reported. Benzotriazole carboxyl group activation of the 6-chloro-fluorophore enabled quick labeling of free and Fmoc-protected amino acids. The photophysical properties of the compounds obtained include high quantum yields in solvents of different polarity: water, methanol, acetonitrile and hexane.

Supplementary files

Publication details

The article was received on 10 Sep 2009, accepted on 11 Jan 2010 and first published on 27 Jan 2010

Article type: Paper

DOI: 10.1039/C000684J

Citation: Org. Biomol. Chem., 2010,8, 1296-1300

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Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative

A. R. Katritzky, S. Ozcan and E. Todadze, Org. Biomol. Chem., 2010, 8, 1296
DOI: 10.1039/C000684J
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Organic & Biomolecular Chemistry

Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative

Abstract

Supplementary files

Publication details

Synthesis and fluorescence of the new environment-sensitive fluorophore 6-chloro-2,3-naphthalimide derivative

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