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Issue 8, 2010
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Synthesis of the structure proposed for the natural allenic antibiotic scorodonin

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Abstract

The structure proposed for scorodonin, a natural allenyne with significant antibacterial and antifungal activities, was synthesized through an enantioselective route. The spectroscopic data of the synthetic allenyne are generally consistent with those reported for the natural one, but slight yet definite differences were observed in 13C NMR.

Graphical abstract: Synthesis of the structure proposed for the natural allenic antibiotic scorodonin

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Publication details

The article was received on 13 Jan 2010, accepted on 08 Feb 2010 and first published on 26 Feb 2010


Article type: Paper
DOI: 10.1039/C000481B
Citation: Org. Biomol. Chem., 2010,8, 1905-1909
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    Synthesis of the structure proposed for the natural allenic antibiotic scorodonin

    Y. Jian and Y. Wu, Org. Biomol. Chem., 2010, 8, 1905
    DOI: 10.1039/C000481B

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