Synthesis and biological evaluation of a triazole-based library of pyrido[2,3-d]pyrimidines as FGFR3 tyrosine kinase inhibitors†
Abstract
A library of pyrido[2,3-d]pyrimidines was designed as
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* Corresponding authors
a
Université Paris Descartes, UMR 8601-CNRS, 45 rue des Saints-Pères, France
E-mail:
yves.le-merrer@parisdescartes.fr, patricia.busca@parisdescartes.fr
Fax: + 33-142868387
Tel: + 33-142862176
b
CNRS UMR144, Institut Curie, 26 rue d'Ulm, France
E-mail:
francois.radvanyi@curie.fr
Fax: + 33-156246349
Tel: +33-156246339
c
Université Paris Descartes, INSERM U781, Hôpital Necker-Enfants Malades, 149 rue de Sèvres, France
E-mail:
laurence.legeai-mallet@inserm.fr
Fax: + 33-1473485 14
Tel: + 33-144494000 ext 97833/97830
A library of pyrido[2,3-d]pyrimidines was designed as
L. Le Corre, A. Girard, J. Aubertin, F. Radvanyi, C. Benoist-Lasselin, A. Jonquoy, E. Mugniery, L. Legeai-Mallet, P. Busca and Y. Le Merrer, Org. Biomol. Chem., 2010, 8, 2164 DOI: 10.1039/B923882D
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