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Issue 12, 2010
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Calixarenes: from biomimetic receptors to multivalent ligands for biomolecular recognition

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Abstract

Calixarenes are versatile platforms for the design and synthesis of molecular receptors and multivalent ligands that are able to mimic or affect specific biological functions. This review illustrates examples spanning the recognition of small peptides and carbohydrates to ion transport through membranes, biomimetic catalysis, DNA condensation and cell transfection, protein binding, sensing and inhibition, and gives perspectives for using calixarene macrocycles in bio-supramolecular chemistry.

Graphical abstract: Calixarenes: from biomimetic receptors to multivalent ligands for biomolecular recognition

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Publication details

The article was received on 16 Apr 2010, accepted on 20 Jul 2010 and first published on 20 Sep 2010


Article type: Perspective
DOI: 10.1039/C0NJ00285B
Citation: New J. Chem., 2010,34, 2715-2728
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    Calixarenes: from biomimetic receptors to multivalent ligands for biomolecular recognition

    F. Sansone, L. Baldini, A. Casnati and R. Ungaro, New J. Chem., 2010, 34, 2715
    DOI: 10.1039/C0NJ00285B

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