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Issue 18, 2010
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Detection of waterborne parasites using field-portable and cost-effective lensfree microscopy

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Abstract

Protection of human health and well-being through water quality management is an important goal for both the developed and the developing parts of the world. In the meantime, insufficient disinfection techniques still fail to eliminate pathogenic contaminants in freshwater as well as recreational water resources. Therefore, there is a significant need for screening of water quality to prevent waterborne outbreaks and incidents of water-related diseases. Toward this end, here we investigate the use of a field-portable and cost-effective lensfree holographic microscope to image and detect pathogenic protozoan parasites such as Giardia Lamblia and Cryptosporidium Parvum at low concentration levels. This compact lensless microscope (O. Mudanyali et al., Lab Chip, 2010, 10, 1417–1428), weighing ∼46 grams, achieves a numerical aperture of ∼0.1–0.2 over an imaging field of view that is more than an order of magnitude larger than a typical 10X objective lens, and therefore may provide an important high-throughput analysis tool for combating waterborne diseases especially in resource limited settings.

Graphical abstract: Detection of waterborne parasites using field-portable and cost-effective lensfree microscopy

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Publication details

The article was received on 31 Mar 2010, accepted on 06 Jul 2010, published on 09 Aug 2010 and first published online on 09 Aug 2010


Article type: Paper
DOI: 10.1039/C004829A
Citation: Lab Chip, 2010,10, 2419-2423
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    Detection of waterborne parasites using field-portable and cost-effective lensfree microscopy

    O. Mudanyali, C. Oztoprak, D. Tseng, A. Erlinger and A. Ozcan, Lab Chip, 2010, 10, 2419
    DOI: 10.1039/C004829A

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