Duke University, Department of Mechanical Engineering and Materials Science, Center for Biologically Inspired Materials and Material Systems (CBIMMS), Durham, USA
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Lab Chip, 2010,10, 2108-2114
03 Mar 2010,
26 May 2010
First published online
17 Jun 2010
We present theoretical, numerical, and experimental analyses on the non-linear dynamic behavior of superparamagnetic beads exposed to a periodic array of micro-magnets and an external rotating field. The agreement between theoretical and experimental results revealed that non-linear magnetic forcing dynamics are responsible for transitions between phase-locked orbits, sub-harmonic orbits, and closed orbits, representing different mobility regimes of colloidal beads. These results suggest that the non-linear behavior can be exploited to construct a novel colloidal separation device that can achieve effectively infinite separation resolution for different types of beads, by exploiting minor differences in their bead's properties. We also identify a unique set of initial conditions, which we denote the “devil's gate” which can be used to expeditiously identify the full range of mobility for a given bead type.
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