Low-cost rapid prototyping of flexible microfluidic devices using a desktop digital craft cutter

Po Ki Yuen; Vasiliy N. Goral

doi:10.1039/B918089C

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Lab on a Chip

Issue 3, 2010

Miniaturisation for chemistry, physics, biology, materials science and bioengineering

Impact Factor 5.67 24 Issues per Year Indexed in MEDLINE

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Low-cost rapid prototyping of flexible microfluidic devices using a desktop digital craft cutter

Po Ki Yuen*^a and Vasiliy N. Goral^a

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Science & Technology, Corning Incorporated, Corning, USA
E-mail: yuenp@corning.com ;
Fax: +1 (607) 974-5957 ;
Tel: +1 (607) 974-9680

Lab Chip, 2010,10, 384-387

DOI: 10.1039/B918089C
Received 03 Sep 2009, Accepted 09 Nov 2009
First published online 24 Nov 2009

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Low-cost and straight forward rapid prototyping of flexible microfluidic devices using a desktop digital craft cutter is presented. This rapid prototyping method can consistently achieve microchannels as thin as 200 µm in width and can be used to fabricate three-dimensional (3D) microfluidic devices using only double-sided pressure sensitive adhesive (PSA) tape and laser printer transparency film. Various functional microfluidic devices are demonstrated with this rapid prototyping method. The complete fabrication process from device design concept to working device can be completed in minutes without the need of expensive equipment.

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Overnight C3A cell culture protocol used in the study
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