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A comparison between HPLC-dynamic reaction cell-ICP-MS and HPLC-sector field-ICP-MS for the detection of glutathione-trapped reactive drug metabolites using clozapine as a model compound

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Corresponding authors
a
Ghent University, Department of Analytical Chemistry, Krijgslaan 281 - S12, Ghent, Belgium
E-mail: Lieve.Balcaen@UGent.be
b
Johnson & Johnson Pharmaceutical R&D, Global Preclinical Development, Turnhoutseweg 30, Beerse, Belgium
J. Anal. At. Spectrom., 2010,25, 419-425

DOI: 10.1039/B921638C
Received 21 Oct 2009, Accepted 19 Jan 2010
First published online 27 Jan 2010

This article is part of themed collection: 2010 Young Analytical Scientists
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Journal of Analytical Atomic Spectrometry - Information Point