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Issue 11, 2010
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Organocatalytic strategies for the asymmetric functionalization of indoles

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Abstract

The desire for new synthetic methodologies for the rapid construction of enantiomerically pure substituted indole has been a fruitful driving force for chemical research in the last few years. This research line has produced a stunning array of enantioselective technologies either metal or organocatalyzed. This critical review documents the development of organocatalytic indole alkylation strategies, until the end of 2009 (127 references).

Graphical abstract: Organocatalytic strategies for the asymmetric functionalization of indoles

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Publication details

The article was received on 03 Mar 2010 and first published on 17 Sep 2010


Article type: Critical Review
DOI: 10.1039/B923063G
Citation: Chem. Soc. Rev., 2010,39, 4449-4465
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    Organocatalytic strategies for the asymmetric functionalization of indoles

    G. Bartoli, G. Bencivenni and R. Dalpozzo, Chem. Soc. Rev., 2010, 39, 4449
    DOI: 10.1039/B923063G

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