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Issue 8, 2010
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Carbohydrate functionalized carbon nanotubes and their applications

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Abstract

Carbon nanotubes (CNTs) have attracted tremendous attention in biomedical applications due to their molecular size and unique properties. This tutorial review summarizes the strategies to functionalize CNTs with bioactive carbohydrates, which improve their solubility, biocompatibility and biofunctionalities while preserving their desired properties. In addition, studies on the usage of carbohydrate functionalized CNTs to detect bacteria, to bind to specific lectins, to deliver glycomimetic drug molecules into cells and to probe cellular activities as biosensors are reviewed. Improvement in biocompatibility and introduction of bio-functionalities by integration of carbohydrate with CNTs are paving the way to glyconanotechnology and may provide new tools for glycobiological studies.

Graphical abstract: Carbohydrate functionalized carbon nanotubes and their applications

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Publication details

The article was received on 18 Sep 2009 and first published on 28 Jun 2010


Article type: Tutorial Review
DOI: 10.1039/B919525B
Citation: Chem. Soc. Rev., 2010,39, 2925-2934
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    Carbohydrate functionalized carbon nanotubes and their applications

    B. K. Gorityala, J. Ma, X. Wang, P. Chen and X. Liu, Chem. Soc. Rev., 2010, 39, 2925
    DOI: 10.1039/B919525B

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