Jump to main content
Jump to site search

Issue 8, 2010
Previous Article Next Article

The carbocation continuum in terpene biosynthesis—where are the secondary cations?

Author affiliations

Abstract

In this tutorial review, structures encountered in carbocation cascade polycyclization reactions leading to terpene natural products are surveyed. The nature of delocalization in these carbocations is discussed in detail. For select cases, the ability of functional groups in enzyme active sites to modulate this delocalization is discussed. In addition to carbocation intermediates, cationic transition state structures are also described.

Graphical abstract: The carbocation continuum in terpene biosynthesis—where are the secondary cations?

Back to tab navigation

Publication details

The article was received on 28 Sep 2009 and first published on 04 May 2010


Article type: Tutorial Review
DOI: 10.1039/B917107J
Citation: Chem. Soc. Rev., 2010,39, 2847-2854
  •   Request permissions

    The carbocation continuum in terpene biosynthesis—where are the secondary cations?

    D. J. Tantillo, Chem. Soc. Rev., 2010, 39, 2847
    DOI: 10.1039/B917107J

Search articles by author

Spotlight

Advertisements