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Issue 7, 2010
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Water-soluble fluorescent conjugated polymers and their interactions with biomacromolecules for sensitive biosensors

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Abstract

Over the past decades, water-soluble conjugated polymers (CPs) have gained increasing attention as optical platforms for sensitive detection of biomacromolecules (DNA, protein and cell) due to the amplification of fluorescent signals. To meet the requirement for high throughput assays, chip and microarray techniques based on CPs have also been developed. Very recently, fluorescence imaging in vivo and at the cellular level have also been successfully accomplished using these water-soluble CPs. In this tutorial review, we provide a brief review of the synthesis and optical properties of CPs, focusing especially on their applications in biosensors and cell imaging.

Graphical abstract: Water-soluble fluorescent conjugated polymers and their interactions with biomacromolecules for sensitive biosensors

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Publication details

The article was received on 22 Oct 2009 and first published on 05 Mar 2010


Article type: Tutorial Review
DOI: 10.1039/B909065G
Citation: Chem. Soc. Rev., 2010,39, 2411-2419
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    Water-soluble fluorescent conjugated polymers and their interactions with biomacromolecules for sensitive biosensors

    X. Feng, L. Liu, S. Wang and D. Zhu, Chem. Soc. Rev., 2010, 39, 2411
    DOI: 10.1039/B909065G

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