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Issue 4, 2010
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Thiol-click chemistry: a multifaceted toolbox for small molecule and polymer synthesis

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Abstract

The merits of thiol-click chemistry and its potential for making new forays into chemical synthesis and materials applications are described. Since thiols react to high yields under benign conditions with a vast range of chemical species, their utility extends to a large number of applications in the chemical, biological, physical, materials and engineering fields. This critical review provides insight into emerging venues for application as well as new mechanistic understanding of this exceptional chemistry in its many forms (81 references).

Graphical abstract: Thiol-click chemistry: a multifaceted toolbox for small molecule and polymer synthesis

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Publication details

The article was received on 04 Sep 2009 and first published on 09 Feb 2010


Article type: Critical Review
DOI: 10.1039/B901979K
Citation: Chem. Soc. Rev., 2010,39, 1355-1387
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    Thiol-click chemistry: a multifaceted toolbox for small molecule and polymer synthesis

    C. E. Hoyle, A. B. Lowe and C. N. Bowman, Chem. Soc. Rev., 2010, 39, 1355
    DOI: 10.1039/B901979K

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