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Issue 31, 2010
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Stacked graphene nanofibers for electrochemical oxidation of DNA bases

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Abstract

In this article, we show that stacked graphene nanofibers (SGNFs) demonstrate superior electrochemical performance for oxidation of DNA bases over carbon nanotubes (CNTs). This is due to an exceptionally high number of accessible graphene sheet edges on the surface of the nanofibers when compared to carbon nanotubes, as shown by transmission electron microscopy and Raman spectroscopy. The oxidation signals of adenine, guanine, cytosine, and thymine exhibit two to four times higher currents than on CNT-based electrodes. SGNFs also exhibit higher sensitivity than do edge-plane pyrolytic graphite, glassy carbon, or graphite microparticle-based electrodes. We also demonstrate that influenza A(H1N1)-related strands can be sensitively oxidized on SGNF-based electrodes, which could therefore be applied to label-free DNA analysis.

Graphical abstract: Stacked graphene nanofibers for electrochemical oxidation of DNA bases

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Publication details

The article was received on 14 Apr 2010, accepted on 05 May 2010 and first published on 07 Jun 2010


Article type: Paper
DOI: 10.1039/C0CP00213E
Citation: Phys. Chem. Chem. Phys., 2010,12, 8943-8947
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    Stacked graphene nanofibers for electrochemical oxidation of DNA bases

    A. Ambrosi and M. Pumera, Phys. Chem. Chem. Phys., 2010, 12, 8943
    DOI: 10.1039/C0CP00213E

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