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Issue 38, 2010
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Microfluidic characterization of sustained solute release from porous supraparticles

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Abstract

We present a novel microfluidic technique for precise characterization of controlled release of solute from porous latex supraparticles in a laminar flow environment. Dye-infused supraparticles are fabricated via dry self-assembly method using droplet templates dispensed on superhydrophobic substrates. A water-soluble dye is used as a model compound, the release rate of which is measured colorimetrically. The sustained release rates of dye from supraparticles and dye pellets are quantified and compared to common diffusion/dissolution mass transfer models. The results illustrate the potential of microfluidics as a tool in monitoring controlled release process and the role of the uniformly porous supraparticle matrix for the prolonged continuous solute delivery.

Graphical abstract: Microfluidic characterization of sustained solute release from porous supraparticles

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Publication details

The article was received on 04 Apr 2010, accepted on 02 Aug 2010 and first published on 28 Aug 2010


Article type: Paper
DOI: 10.1039/C0CP00119H
Citation: Phys. Chem. Chem. Phys., 2010,12, 11975-11983
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    Microfluidic characterization of sustained solute release from porous supraparticles

    V. Rastogi, K. P. Velikov and O. D. Velev, Phys. Chem. Chem. Phys., 2010, 12, 11975
    DOI: 10.1039/C0CP00119H

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