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Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, and State Key Laboratory of Biotherapy, West China Medical School, Sichuan University, 29 Wangjiang Road, Chengdu 610064, P.R. China
E-mail: jsyou@scu.edu.cn
; Fax: (+86) 28-85412203
Chem. Commun., 2010,46, 9049-9051
DOI:
10.1039/C0CC03772A
Received
10 Sep 2010,
Accepted
11 Oct 2010
First published online
04 Nov 2010
The copper-catalyzed decarboxylative reactions of alkynyl carboxylic acids with aryl halides were performed under relatively mild reaction conditions. Benzofurans could be further prepared smoothly by a one-pot domino protocol on the basis of decarboxylative cross-coupling of 2-iodophenol.