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Issue 48, 2010
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Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

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Abstract

Statistical correlation of mass spectrum peak broadening with product dispersity in protein conjugation reactions allows more detailed characterization of putative therapeutic conjugates.

Graphical abstract: Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

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Publication details

The article was received on 23 Aug 2010, accepted on 29 Sep 2010 and first published on 29 Oct 2010


Article type: Communication
DOI: 10.1039/C0CC03420G
Citation: Chem. Commun., 2010,46, 9119-9121
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    Analysis of the dispersity in carbohydrate loading of synthetic glycoproteins using MALDI-TOF mass spectrometry

    M. K. Patel, B. Vijayakrishnan, J. R. Koeppe, J. M. Chalker, K. J. Doores and B. G. Davis, Chem. Commun., 2010, 46, 9119
    DOI: 10.1039/C0CC03420G

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