Issue 46, 2010
From the journal:

Chemical Communications

Enzyme-assisted binary probe for sensitive detection ofRNA and DNA†

Yulia V. Gerasimova,*a   Sadia Pecka  and  Dmitry M. Kolpashchikova  

* Corresponding authors

a Chemistry Department, University of Central Florida, Orlando, USA
E-mail: ygerasim@mail.ucf.edu
Fax: +1-407-823-2252
Tel: +1 407-823-5953

Abstract

The new enzyme-assisted assay for DNA/RNA detection provides real-time fluorescent signal readout along with low limit of detection and high discrimination power toward a single-base substitution. Requiring only two new unmodified DNA oligonucleotides for the detection of each new analyte, the assay is an efficient tool for low-cost analysis of multiple analytes.

Graphical abstract: Enzyme-assisted binary probe for sensitive detection of RNA and DNA

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Article information

DOI
https://doi.org/10.1039/C0CC03248D
Article type
Communication
Submitted
13 Aug 2010
Accepted
05 Oct 2010
First published
21 Oct 2010

Chem. Commun., 2010,46, 8761-8763

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Enzyme-assisted binary probe for sensitive detection of RNA and DNA

Y. V. Gerasimova, S. Peck and D. M. Kolpashchikov, Chem. Commun., 2010, 46, 8761 DOI: 10.1039/C0CC03248D

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