Issue 41, 2010
From the journal:

Chemical Communications

Aptamer-induced self-assembly of a NIR-emissive platinum(ii) terpyridyl complex for label- and immobilization-free detection oflysozyme and thrombin†

Margaret Ching-Lam Yeung,a   Keith Man-Chung Wong,a   Yuk Kai Tiu Tsanga  and  Vivian Wing-Wah Yam*a  

* Corresponding authors

a Institute of Molecular Functional Materials (Areas of Excellence Scheme, University Grants Committee, Hong Kong) and Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China
E-mail: wwyam@hku.hk
Fax: +852 2857 1586
Tel: +852 2859 2153

Abstract

With the aptamer-induced self-assembly feature of NIR-emissive platinum(II) terpyridyl complex, a “proof-of-principle” concept in label- and immobilization-free probing strategies of lysozyme and thrombin has been demonstrated with good selectivity and specificity.

Graphical abstract: Aptamer-induced self-assembly of a NIR-emissive platinum(ii) terpyridyl complex for label- and immobilization-free detection of lysozyme and thrombin

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Article information

DOI
https://doi.org/10.1039/C0CC02631J
Article type
Communication
Submitted
17 Jul 2010
Accepted
01 Sep 2010
First published
24 Sep 2010

Chem. Commun., 2010,46, 7709-7711

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Aptamer-induced self-assembly of a NIR-emissive platinum(II) terpyridyl complex for label- and immobilization-free detection of lysozyme and thrombin

M. C. Yeung, K. M. Wong, Y. K. T. Tsang and V. W. Yam, Chem. Commun., 2010, 46, 7709 DOI: 10.1039/C0CC02631J

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