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Issue 45, 2010
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Synthesis of a novel magnetic drug delivery system composed of doxorubicin-conjugated Fe3O4 nanoparticle cores and a PEG-functionalized porous silica shell

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Abstract

Coating a layer of PEG functionalized porous silica shell onto doxorubicin-conjugated Fe3O4 nanoparticles, we demonstrated, provides a number of combined advantages in view of the magnetic carrier's therapeutic functionality to treat tumors.

Graphical abstract: Synthesis of a novel magnetic drug delivery system composed of doxorubicin-conjugated Fe3O4 nanoparticle cores and a PEG-functionalized porous silica shell

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Publication details

The article was received on 15 Jul 2010, accepted on 24 Sep 2010 and first published on 12 Oct 2010


Article type: Communication
DOI: 10.1039/C0CC02577A
Citation: Chem. Commun., 2010,46, 8633-8635
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    Synthesis of a novel magnetic drug delivery system composed of doxorubicin-conjugated Fe3O4 nanoparticle cores and a PEG-functionalized porous silica shell

    F. Chen, L. Zhang, Q. Chen, Y. Zhang and Z. Zhang, Chem. Commun., 2010, 46, 8633
    DOI: 10.1039/C0CC02577A

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