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Issue 43, 2010
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Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins

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Abstract

A tag-and-modify strategy allows the practical synthesis of homogenous fluorinated glyco-amino acids, peptides and proteins carrying a fluorine label in the sugar and allows access to first examples of directly radiolabelled ([18F]-glyco)proteins.

Graphical abstract: Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins

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Publication details

The article was received on 25 May 2010, accepted on 02 Jul 2010 and first published on 16 Aug 2010


Article type: Communication
DOI: 10.1039/C0CC01576H
Citation: Chem. Commun., 2010,46, 8142-8144
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    Fluoroglycoproteins: ready chemical site-selective incorporation of fluorosugars into proteins

    O. Boutureira, F. D'Hooge, M. Fernández-González, G. J. L. Bernardes, M. Sánchez-Navarro, J. R. Koeppe and B. G. Davis, Chem. Commun., 2010, 46, 8142
    DOI: 10.1039/C0CC01576H

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