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Issue 36, 2010
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HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

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Abstract

We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

Graphical abstract: HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

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Publication details

The article was received on 21 Apr 2010, accepted on 12 Jul 2010 and first published on 23 Aug 2010


Article type: Communication
DOI: 10.1039/C0CC01041C
Citation: Chem. Commun., 2010,46, 6684-6686
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    HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

    J. Huang, J. Xie, K. Chen, L. Bu, S. Lee, Z. Cheng, X. Li and X. Chen, Chem. Commun., 2010, 46, 6684
    DOI: 10.1039/C0CC01041C

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