Issue 18, 2010
From the journal:

Chemical Communications

Using graphene to protect DNA from cleavage during cellular delivery†

Chun-Hua Lu,a   Chun-Ling Zhu,c   Juan Li,a   Jing-Jing Liu,a   Xi Chen*ab  and  Huang-Hao Yang*a  

* Corresponding authors

a The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350002, P.R. China
E-mail: hhyang@fzu.edu.cn
Fax: 8659122866135
Tel: 8659122866135

b State Key Laboratory of Marine Environmental Science, Xiamen University, 361005 Xiamen, P.R. China

c The First Institute of Oceanography, SOA, Qingdao, P.R. China

Abstract

We have proved that functionalized nanoscale graphene oxide can protect oligonucleotides from enzymatic cleavage and efficiently deliver oligonucleotides into cells.

Graphical abstract: Using graphene to protect DNA from cleavage during cellular delivery

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Article information

DOI
https://doi.org/10.1039/B926893F
Article type
Communication
Submitted
23 Dec 2009
Accepted
02 Mar 2010
First published
29 Mar 2010

Chem. Commun., 2010,46, 3116-3118

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Using graphene to protect DNA from cleavage during cellular delivery

C. Lu, C. Zhu, J. Li, J. Liu, X. Chen and H. Yang, Chem. Commun., 2010, 46, 3116 DOI: 10.1039/B926893F

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