Spontaneous symmetry breaking during interrupted crystallization of an axially chiral amino acid derivative

Mark A. Sephton; Christopher R. Emerson; Lev N. Zakharov; Paul R. Blakemore

doi:10.1039/B922028C

Spontaneous symmetry breaking during interrupted crystallization of an axially chiral amino acid derivative

Mark A. Sephton,^a Christopher R. Emerson,^a Lev N. Zakharov^a and Paul R. Blakemore*^a

* Corresponding authors

^a Department of Chemistry, Oregon State University, Corvallis, Oregon 97331-4003, USA
E-mail: paul.blakemore@science.oregonstate.edu
Fax: +1 541 737 2062
Tel: +1 541 737 6728

Abstract

High net enantiomeric excess was observed for crystal collections obtained by crystallization of the TFA salt of a configurationally stable yet racemic axially chiral amidoamine in EtOH solution with or without stirring (up to >99% ee at ≤15% crystallization).

Supplementary files

Publication details

The article was received on 21 Oct 2009, accepted on 04 Feb 2010 and first published on 19 Feb 2010

Article type: Communication

DOI: 10.1039/B922028C

Citation: Chem. Commun., 2010,46, 2094-2096

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Spontaneous symmetry breaking during interrupted crystallization of an axially chiral amino acid derivative

M. A. Sephton, C. R. Emerson, L. N. Zakharov and P. R. Blakemore, Chem. Commun., 2010, 46, 2094
DOI: 10.1039/B922028C
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Chemical Communications

Spontaneous symmetry breaking during interrupted crystallization of an axially chiral amino acid derivative

Abstract

Supplementary files

Publication details

Spontaneous symmetry breaking during interrupted crystallization of an axially chiral amino acid derivative

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