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Issue 7, 2010
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Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties

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Abstract

A new class of biodegradable materials was prepared by combining polyethylene glycol, heparin, and a matrix metalloproteinase-cleavable peptide sequence into a well-defined hydrogel network which mimics native extracellular matrices in its ability to provide mechanical support and chemical signals as well as elicit a dynamic reciprocal response.

Graphical abstract: Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties

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Publication details

The article was received on 16 Oct 2009, accepted on 25 Nov 2009 and first published on 16 Dec 2009


Article type: Communication
DOI: 10.1039/B921616B
Citation: Chem. Commun., 2010,46, 1141-1143
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    Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties

    M. V. Tsurkan, K. R. Levental, U. Freudenberg and C. Werner, Chem. Commun., 2010, 46, 1141
    DOI: 10.1039/B921616B

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