Jump to main content
Jump to site search

Issue 16, 2010
Previous Article Next Article

Probing biomolecular interactions using surface enhanced Raman spectroscopy: label-free protein detection using a G-quadruplex DNA aptamer

Author affiliations

Abstract

We demonstrate a strategy for label-free protein detection through monitoring the Surface Enhanced Raman Spectrum of an aptamer probe attached to a gold nanoshell. Low limit of detection and minimal non-specific binding show potential for in vitro and in vivo assays.

Graphical abstract: Probing biomolecular interactions using surface enhanced Raman spectroscopy: label-free protein detection using a G-quadruplex DNA aptamer

Back to tab navigation

Supplementary files

Publication details

The article was received on 13 Oct 2009, accepted on 05 Feb 2010 and first published on 02 Mar 2010


Article type: Communication
DOI: 10.1039/B920941G
Citation: Chem. Commun., 2010,46, 2799-2801
  •   Request permissions

    Probing biomolecular interactions using surface enhanced Raman spectroscopy: label-free protein detection using a G-quadruplex DNA aptamer

    M. A. Ochsenkühn and C. J. Campbell, Chem. Commun., 2010, 46, 2799
    DOI: 10.1039/B920941G

Search articles by author

Spotlight

Advertisements