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Issue 3, 2010
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A pH-driven DNA switch based on the A+·G mispair

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Abstract

A new approach to the development of pH-driven DNA switches is presented. Here, the improved stability of the A·G mispair under slightly acidic conditions is exploited. The temperature tunability and the potential generality of the approach are discussed.

Graphical abstract: A pH-driven DNA switch based on the A+·G mispair

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Publication details

The article was received on 09 Sep 2009, accepted on 05 Nov 2009 and first published on 25 Nov 2009


Article type: Communication
DOI: 10.1039/B918725A
Citation: Chem. Commun., 2010,46, 418-420
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    A pH-driven DNA switch based on the A+·G mispair

    J. A. Lee and M. C. DeRosa, Chem. Commun., 2010, 46, 418
    DOI: 10.1039/B918725A

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