Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides

Lynda Cosgrave; Marc Devocelle; Robert J. Forster; Tia E. Keyes

doi:10.1039/B918611E

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Chemical Communications

Issue 1, 2010

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Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides

Lynda Cosgrave , Marc Devocelle , Robert J. Forster and Tia E. Keyes

Chem. Commun., 2010, 46, 103-105

DOI: 10.1039/B918611E
Received 09 Sep 2009, Accepted 06 Nov 2009
First published on the web 19 Nov 2009

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The capacity of ruthenium polypyridyl complexes as probes for combined confocal luminescence and resonance Raman imaging, enabled by their large Stokes shift, is demonstrated for a novel membrane sensitive Ru(II) polypyridyl peptide. Confocal luminescence and resonance Raman imaging provides complementary information about the membrane phospholipid regions of the cell and the location of the dye within the cell.

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Chemical Communications

Multimodal cell imaging by ruthenium polypyridyl labelled cell penetrating peptides

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