Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

José Alemán; Virginia del Solar; Carmen Navarro-Ranninger

doi:10.1039/B917758B

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Chemical Communications

Issue 3, 2010

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Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

José Alemán , Virginia del Solar and Carmen Navarro-Ranninger

Chem. Commun., 2010, 46, 454-456

DOI: 10.1039/B917758B
Received 28 Aug 2009, Accepted 21 Oct 2009
First published on the web 11 Nov 2009

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An efficient cyclization of alkyne-acids to enol-lactones catalyzed by anticancer platinum(II) and platinum(IV) compounds is described. These compounds are not only DNA-binding complexes; they can also catalyze reactions in solvents such as acetone, methanol, water or blood plasma.

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Chemical Communications

Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

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